Alcohol

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Yes, but many, many more people take alcohol than take drugs, or even combinations of.
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Which is why it causes as much damage as it does and why it gets a battering on here that other drugs don't.

I appreciate that that you enjoy it and can handle it, but it is a vile drug when misused.

That said, I am of the opinion that it would impossible to get rid of. It's a major part of the history and heritage of these islands.